increased neuron apoptosis_Gpx1<tm1Kola>/Gpx1<tm1Kola>

http://metadb.riken.jp/0003203I129S2SvPasBALBcCF1Gpx1tm1KolaGpx1tm1KolaGpx1tm1Kola

increased neuron apoptosis_Gpx1<tm1Kola>/Gpx1<tm1Kola>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutathione peroxidase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:104887

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gpx1<tm1Kola>/Gpx1<tm1Kola>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gpx1<tm1Kola>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * BALB/c * CF-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neuron apoptosis
  http://purl.obolibrary.org/obo/MP_0003203

文献

http://purl.org/net/cito/citesAsAuthority

• Nicole J. Flentjar, et.al., Mice lacking glutathione peroxidase-1 activity show increased TUNEL staining and an accelerated inflammatory response in brain following a cold-induced injury., Experimental neurology, 2002, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/12429206
• P J. Crack, et.al., Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury., Journal of neurochemistry, 2001, 78
  http://rdf.ncbi.nlm.nih.gov/pubmed/11579147