decreased neuron apoptosis_Apaf1<fog>/Apaf1<Gt(IRESBetageo)XIX18Pgr>

http://metadb.riken.jp/0003204I129S1Sv129S6SvEvTac129X1SvJC3HHeJNMRIApaf1fogApaf1GtIRESBetageoXIX18PgrApaf1fogApaf1GtIRESBetageoXIX18Pgr

decreased neuron apoptosis_Apaf1<fog>/Apaf1<Gt(IRESBetageo)XIX18Pgr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• apoptotic peptidase activating factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1306796

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apaf1<fog>/Apaf1<Gt(IRESBetageo)XIX18Pgr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apaf1<fog>|Apaf1<Gt(IRESBetageo)XIX18Pgr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeJ * NMRI

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased neuron apoptosis
  http://purl.obolibrary.org/obo/MP_0003204

文献

http://purl.org/net/cito/citesAsAuthority

• Ronald W. Oppenheim, et.al., Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18256270