decreased neuron apoptosis_Map2k4<tm1Ctr>/Map2k4<tm1Ctr>,Map2k7<tm1Rjd>/Map2k7<tm1Rjd>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0003204IC57BL6CBAMap2k4tm1CtrMap2k4tm1CtrMap2k7tm1RjdMap2k7tm1RjdTgCAGcreEsr15Amc0TgCAGcreEsr15AmcMap2k7tm1RjdMap2k4tm1Ctr

decreased neuron apoptosis_Map2k4<tm1Ctr>/Map2k4<tm1Ctr>,Map2k7<tm1Rjd>/Map2k7<tm1Rjd>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitogen-activated protein kinase kinase 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346869
• mitogen-activated protein kinase kinase 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346871
• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Map2k4<tm1Ctr>/Map2k4<tm1Ctr>,Map2k7<tm1Rjd>/Map2k7<tm1Rjd>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-cre/Esr1*)5Amc|Map2k7<tm1Rjd>|Map2k4<tm1Ctr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased neuron apoptosis
  http://purl.obolibrary.org/obo/MP_0003204

文献

http://purl.org/net/cito/citesAsAuthority

• Sonia. Mazzitelli, et.al., The loss of c-Jun N-terminal protein kinase activity prevents the amyloidogenic cleavage of amyloid precursor protein and the formation of amyloid plaques in vivo., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/22114267