increased cardiomyocyte apoptosis_Gt(ROSA)26Sor<tm2(ATF4)Myz>/Gt(ROSA)26Sor<tm2(ATF4)Myz>,Tg(Myh11-cre/ERT2)1Soff/?

http://metadb.riken.jp/0003222ED2CgAtf4tm11CmadTgMyh11creERT21SofforB6CgAtf4tm11CmadTgMyh11creERT21SoffGtROSA26Sortm2ATF4MyzGtROSA26Sortm2ATF4MyzTgMyh11creERT21SoffGtROSA26Sortm2ATF4MyzTgMyh11creERT21Soff

increased cardiomyocyte apoptosis_Gt(ROSA)26Sor<tm2(ATF4)Myz>/Gt(ROSA)26Sor<tm2(ATF4)Myz>,Tg(Myh11-cre/ERT2)1Soff/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Stefan Offermanns
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819268

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm2(ATF4)Myz>/Gt(ROSA)26Sor<tm2(ATF4)Myz>,Tg(Myh11-cre/ERT2)1Soff/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm2(ATF4)Myz>|Tg(Myh11-cre/ERT2)1Soff

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: D2.Cg-Atf4<tm1.1Cmad> Tg(Myh11-cre/ERT2)1Soff or B6.Cg-Atf4<tm1.1Cmad> Tg(Myh11-cre/ERT2)1Soff

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cardiomyocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0003222

文献

http://purl.org/net/cito/citesAsAuthority

• Masashi. Masuda, et.al., Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells., JCI insight, 2016, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/27812542