increased cardiomyocyte apoptosis_Hdac1<tm1.1Eno>/Hdac1<tm1.1Eno>,Hdac2<tm1.1Eno>/Hdac2<tm1.1Eno>,Tg(Myh6-cre)2182Mds/?

http://metadb.riken.jp/0003222I129SSvEvC57BL6CD1FVBNHdac1tm11EnoHdac1tm11EnoHdac2tm11EnoHdac2tm11EnoTgMyh6cre2182MdsHdac1tm11EnoHdac2tm11EnoTgMyh6cre2182Mds

increased cardiomyocyte apoptosis_Hdac1<tm1.1Eno>/Hdac1<tm1.1Eno>,Hdac2<tm1.1Eno>/Hdac2<tm1.1Eno>,Tg(Myh6-cre)2182Mds/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• histone deacetylase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:108086
• histone deacetylase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097691

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hdac1<tm1.1Eno>/Hdac1<tm1.1Eno>,Hdac2<tm1.1Eno>/Hdac2<tm1.1Eno>,Tg(Myh6-cre)2182Mds/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hdac1<tm1.1Eno>|Hdac2<tm1.1Eno>|Tg(Myh6-cre)2182Mds

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * CD-1 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cardiomyocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0003222

文献

http://purl.org/net/cito/citesAsAuthority

• Rusty L. Montgomery, et.al., Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility., Genes & development, 2007, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/17639084