loss of hippocampal neurons_Nos2<tm1Lau>/Nos2<tm1Lau>,Tg(APPSWE)2576Kha/0

http://metadb.riken.jp/0003240I129P2OlaHsdC57BL6SJLNos2tm1LauNos2tm1LauTgAPPSWE2576Kha0TgAPPSWE2576KhaNos2tm1Lau

loss of hippocampal neurons_Nos2<tm1Lau>/Nos2<tm1Lau>,Tg(APPSWE)2576Kha/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nitric oxide synthase 2, inducible
  http://metadb.riken.jp/db/mgi_rdf/MGI:97361
• transgene insertion 2576, Karen Hsiao Ashe
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385632

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nos2<tm1Lau>/Nos2<tm1Lau>,Tg(APPSWE)2576Kha/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APPSWE)2576Kha|Nos2<tm1Lau>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• loss of hippocampal neurons
  http://purl.obolibrary.org/obo/MP_0003240

文献

http://purl.org/net/cito/citesAsAuthority

• Carol A. Colton, et.al., The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP., Journal of Alzheimer's disease : JAD, 2008, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19096157