loss of dopaminergic neurons_Vps35<Gt(RRK261)Byg>/Vps35<+>

http://metadb.riken.jp/0003244B6129P2Vps35GtRRK261BygVps35GtRRK261BygVps35Vps35GtRRK261BygVps35

loss of dopaminergic neurons_Vps35<Gt(RRK261)Byg>/Vps35<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• VPS35 retromer complex component
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890467

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Vps35<Gt(RRK261)Byg>/Vps35<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vps35<Gt(RRK261)Byg>|Vps35<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129P2-Vps35<Gt(RRK261)Byg>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• loss of dopaminergic neurons
  http://purl.obolibrary.org/obo/MP_0003244

文献

http://purl.org/net/cito/citesAsAuthority

• Fu-Lei. Tang, et.al., VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/26203154