loss of dopaminergic neurons_Grn<tm1Far>/Grn<tm1Far>,Tg(ITGAM-cre)2781Gkl/0

http://metadb.riken.jp/0003244I129S4SvJaeC57BL6CBAFVBNGrntm1FarGrntm1FarTgITGAMcre2781Gkl0Grntm1FarTgITGAMcre2781Gkl

loss of dopaminergic neurons_Grn<tm1Far>/Grn<tm1Far>,Tg(ITGAM-cre)2781Gkl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2781, George Kollias
  http://metadb.riken.jp/db/mgi_rdf/MGI:3629089
• granulin
  http://metadb.riken.jp/db/mgi_rdf/MGI:95832

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grn<tm1Far>/Grn<tm1Far>,Tg(ITGAM-cre)2781Gkl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Grn<tm1Far>|Tg(ITGAM-cre)2781Gkl

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• loss of dopaminergic neurons
  http://purl.obolibrary.org/obo/MP_0003244

文献

http://purl.org/net/cito/citesAsAuthority

• Lauren Herl. Martens, et.al., Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury., The Journal of clinical investigation, 2012, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/23041626