amyloid beta deposits_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-QPCT)#Tbay/0

http://metadb.riken.jp/0003329B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1QPCTTbayTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgThy1QPCTTbay0TgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1QPCTTbay

amyloid beta deposits_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-QPCT)#Tbay/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Thomas A Bayer
  http://metadb.riken.jp/db/mgi_rdf/MGI:4941714
• transgene insertion 6799, Robert Vassar
  http://metadb.riken.jp/db/mgi_rdf/MGI:3693207

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-QPCT)#Tbay/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas|Tg(Thy1-QPCT)#Tbay

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas Tg(Thy1-QPCT)#Tbay

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• amyloid beta deposits
  http://purl.obolibrary.org/obo/MP_0003329

文献

http://purl.org/net/cito/citesAsAuthority

• Sadim. Jawhar, et.al., Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice., The Journal of biological chemistry, 2011, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/21148560