amyloid beta deposits_Psen1<tm4.1Shn>/Psen1<+>,Tg(PDGFB-APPSwInd)20Lms/0

http://metadb.riken.jp/0003329I129C57BL6C57BL6JDBA2Psen1tm41ShnPsen1TgPDGFBAPPSwInd20Lms0Psen1Psen1tm41ShnTgPDGFBAPPSwInd20Lms

amyloid beta deposits_Psen1<tm4.1Shn>/Psen1<+>,Tg(PDGFB-APPSwInd)20Lms/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• presenilin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202717
• transgene insertion 20, Lennart Mucke
  http://metadb.riken.jp/db/mgi_rdf/MGI:3057146

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Psen1<tm4.1Shn>/Psen1<+>,Tg(PDGFB-APPSwInd)20Lms/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Psen1<+>|Psen1<tm4.1Shn>|Tg(PDGFB-APPSwInd)20Lms

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * C57BL/6J * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• amyloid beta deposits
  http://purl.obolibrary.org/obo/MP_0003329

文献

http://purl.org/net/cito/citesAsAuthority

• Dan. Xia, et.al., Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease., Neuron, 2015, 85
  http://rdf.ncbi.nlm.nih.gov/pubmed/25741723