amyloid beta deposits_Apoe<tm1Unc>/Apoe<tm1Unc>,Clu<tm1Jakh>/Clu<tm1Jakh>,Tg(APPV717F)109Ili/Tg(APPV717F)109Ili

http://metadb.riken.jp/0003329I129P2OlaHsd129S2SvPasApoetm1UncApoetm1UncClutm1JakhClutm1JakhTgAPPV717F109IliTgAPPV717F109IliClutm1JakhTgAPPV717F109IliApoetm1Unc

amyloid beta deposits_Apoe<tm1Unc>/Apoe<tm1Unc>,Clu<tm1Jakh>/Clu<tm1Jakh>,Tg(APPV717F)109Ili/Tg(APPV717F)109Ili

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057
• clusterin
  http://metadb.riken.jp/db/mgi_rdf/MGI:88423
• transgene insertion 109, Ivan Lieberburg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2152038

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Unc>/Apoe<tm1Unc>,Clu<tm1Jakh>/Clu<tm1Jakh>,Tg(APPV717F)109Ili/Tg(APPV717F)109Ili

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Clu<tm1Jakh>|Tg(APPV717F)109Ili|Apoe<tm1Unc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• amyloid beta deposits
  http://purl.obolibrary.org/obo/MP_0003329

文献

http://purl.org/net/cito/citesAsAuthority

• Ronald B. DeMattos, et.al., ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo., Neuron, 2004, 41
  http://rdf.ncbi.nlm.nih.gov/pubmed/14741101