amyloid beta deposits_Apoe<tm2(APOE*3)Mae>/Apoe<tm2(APOE*3)Mae>,Ldlr<tm1(LDLR)Mae>/Ldlr<+>

http://metadb.riken.jp/0003329I129P2OlaHsd129S7SvEvBrdC57BL6Apoetm2APOE3MaeApoetm2APOE3MaeLdlrtm1LDLRMaeLdlrLdlrtm1LDLRMaeApoetm2APOE3MaeLdlr

amyloid beta deposits_Apoe<tm2(APOE*3)Mae>/Apoe<tm2(APOE*3)Mae>,Ldlr<tm1(LDLR)Mae>/Ldlr<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm2(APOE*3)Mae>/Apoe<tm2(APOE*3)Mae>,Ldlr<tm1(LDLR)Mae>/Ldlr<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ldlr<tm1(LDLR)Mae>|Apoe<tm2(APOE*3)Mae>|Ldlr<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• amyloid beta deposits
  http://purl.obolibrary.org/obo/MP_0003329

文献

http://purl.org/net/cito/citesAsAuthority

• Sudi I. Malloy, et.al., Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3., Arteriosclerosis, thrombosis, and vascular biology, 2004, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/12969990