amyloid beta deposits_Gsk3a<tm1.1Tac>/Gsk3a<tm1.1Tac>,Tg(APPV717F)109Ili/0,Tg(Camk2a-cre)#Stl/0

http://metadb.riken.jp/0003329IBALBcC57BLC57BL6NTacGsk3atm11TacGsk3atm11TacTgAPPV717F109Ili0TgCamk2acreStl0TgCamk2acreStlGsk3atm11TacTgAPPV717F109Ili

amyloid beta deposits_Gsk3a<tm1.1Tac>/Gsk3a<tm1.1Tac>,Tg(APPV717F)109Ili/0,Tg(Camk2a-cre)#Stl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 109, Ivan Lieberburg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2152038
• glycogen synthase kinase 3 alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:2152453
• transgene insertion, Susumu Tonegawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:4946945

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gsk3a<tm1.1Tac>/Gsk3a<tm1.1Tac>,Tg(APPV717F)109Ili/0,Tg(Camk2a-cre)#Stl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Camk2a-cre)#Stl|Gsk3a<tm1.1Tac>|Tg(APPV717F)109Ili

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * C57BL * C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• amyloid beta deposits
  http://purl.obolibrary.org/obo/MP_0003329

文献

http://purl.org/net/cito/citesAsAuthority

• David E. Hurtado, et.al., Selectively silencing GSK-3 isoforms reduces plaques and tangles in mouse models of Alzheimer's disease., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22623685