amyloid beta deposits_Tg(Thy1-AppDutch)#Jckr/0,Tg(Thy1-PSEN1*G384A)45Jckr/0

http://metadb.riken.jp/0003329IC57BL6DBA2TgThy1AppDutchJckr0TgThy1PSEN1G384A45Jckr0TgThy1PSEN1G384A45JckrTgThy1AppDutchJckr

amyloid beta deposits_Tg(Thy1-AppDutch)#Jckr/0,Tg(Thy1-PSEN1*G384A)45Jckr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 45, Mathias Jucker
  http://metadb.riken.jp/db/mgi_rdf/MGI:4818997
• transgene insertion, Mathias Jucker
  http://metadb.riken.jp/db/mgi_rdf/MGI:4438880

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Thy1-AppDutch)#Jckr/0,Tg(Thy1-PSEN1*G384A)45Jckr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Thy1-PSEN1*G384A)45Jckr|Tg(Thy1-AppDutch)#Jckr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• amyloid beta deposits
  http://purl.obolibrary.org/obo/MP_0003329

文献

http://purl.org/net/cito/citesAsAuthority

• Martin C. Herzig, et.al., BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic mice., Neuro-degenerative diseases, 2007, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/17596707