amyloid beta deposits_Hdac6<tm1Anfi>/Hdac6<tm1Anfi>,Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/?

http://metadb.riken.jp/0003329IC57BL6Hdac6tm1AnfiHdac6tm1AnfiTgThy1APPSwThy1PSEN1L166P21JckrHdac6tm1AnfiTgThy1APPSwThy1PSEN1L166P21Jckr

amyloid beta deposits_Hdac6<tm1Anfi>/Hdac6<tm1Anfi>,Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• histone deacetylase 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1333752
• transgene insertion 21, Mathias Jucker
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765348

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hdac6<tm1Anfi>/Hdac6<tm1Anfi>,Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hdac6<tm1Anfi>|Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• amyloid beta deposits
  http://purl.obolibrary.org/obo/MP_0003329

文献

http://purl.org/net/cito/citesAsAuthority

• Nambirajan. Govindarajan, et.al., Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease., EMBO molecular medicine, 2013, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/23184605