amyloid beta deposits_Tg(APPSWE)2576Kha/0

http://metadb.riken.jp/0003329IC57BL6SJLTgAPPSWE2576Kha0TgAPPSWE2576Kha

amyloid beta deposits_Tg(APPSWE)2576Kha/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2576, Karen Hsiao Ashe
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385632

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(APPSWE)2576Kha/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APPSWE)2576Kha

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• amyloid beta deposits
  http://purl.obolibrary.org/obo/MP_0003329

文献

http://purl.org/net/cito/citesAsAuthority

• Eileen. McGowan, et.al., Abeta42 is essential for parenchymal and vascular amyloid deposition in mice., Neuron, 2005, 47
  http://rdf.ncbi.nlm.nih.gov/pubmed/16039562
• Takami. Tomiyama, et.al., A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20371804
• Joseph. El Khoury, et.al., Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease., Nature medicine, 2007, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/17351623