amyloid beta deposits_Tg(Thy1-APPLon)2Vln/0

http://metadb.riken.jp/0003329IFVBNTgThy1APPLon2Vln0TgThy1APPLon2Vln

amyloid beta deposits_Tg(Thy1-APPLon)2Vln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2, Fred Van Leuven
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717495

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Thy1-APPLon)2Vln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Thy1-APPLon)2Vln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• amyloid beta deposits
  http://purl.obolibrary.org/obo/MP_0003329

文献

http://purl.org/net/cito/citesAsAuthority

• I. Dewachter, et.al., Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V717I transgenic mice by a different mechanism than mutant presenilin1., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/10964951
• Michael. Willem, et.al., beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic mice., The American journal of pathology, 2004, 165
  http://rdf.ncbi.nlm.nih.gov/pubmed/15509532
• D. Moechars, et.al., Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain., The Journal of biological chemistry, 1999, 274
  http://rdf.ncbi.nlm.nih.gov/pubmed/10037741