increased hepatocellular carcinoma incidence_Cdkn1a<tm1(HBsAg)Xya>/Cdkn1a<+>

http://metadb.riken.jp/0003331EI129S6SvEvTacC57BL6orI129S6SvEvTacBlackSwissCdkn1atm1HBsAgXyaCdkn1aCdkn1aCdkn1atm1HBsAgXya

increased hepatocellular carcinoma incidence_Cdkn1a<tm1(HBsAg)Xya>/Cdkn1a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 1A (P21)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104556

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1a<tm1(HBsAg)Xya>/Cdkn1a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn1a<+>|Cdkn1a<tm1(HBsAg)Xya>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Youliang. Wang, et.al., HBsAg and HBx knocked into the p21 locus causes hepatocellular carcinoma in mice., Hepatology (Baltimore, Md.), 2004, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/14767984