increased hepatocellular carcinoma incidence_Iqgap1<tm1Aber>/Iqgap1<tm1Aber>,Iqgap2<tm1Vs>/Iqgap2<tm1Vs>

http://metadb.riken.jp/0003331I129S4SvJaeIqgap1tm1AberIqgap1tm1AberIqgap2tm1VsIqgap2tm1VsIqgap2tm1VsIqgap1tm1Aber

increased hepatocellular carcinoma incidence_Iqgap1<tm1Aber>/Iqgap1<tm1Aber>,Iqgap2<tm1Vs>/Iqgap2<tm1Vs>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• IQ motif containing GTPase activating protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449975
• IQ motif containing GTPase activating protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1352757

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Iqgap1<tm1Aber>/Iqgap1<tm1Aber>,Iqgap2<tm1Vs>/Iqgap2<tm1Vs>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Iqgap2<tm1Vs>|Iqgap1<tm1Aber>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Valentina A. Schmidt, et.al., Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent., Molecular and cellular biology, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18180285