increased hepatocellular carcinoma incidence_Apc<Min>/Apc<tm1Tno>,Ctnnb1<tm4.1Wbm>/Ctnnb1<+>

http://metadb.riken.jp/0003331I129Sv129P2OlaHsd129S4SvJaeC57BL6ApcMinApctm1TnoCtnnb1tm41WbmCtnnb1Apctm1TnoApcMinCtnnb1Ctnnb1tm41Wbm

increased hepatocellular carcinoma incidence_Apc<Min>/Apc<tm1Tno>,Ctnnb1<tm4.1Wbm>/Ctnnb1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<Min>/Apc<tm1Tno>,Ctnnb1<tm4.1Wbm>/Ctnnb1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apc<tm1Tno>|Apc<Min>|Ctnnb1<+>|Ctnnb1<tm4.1Wbm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Michael. Buchert, et.al., Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo., PLoS genetics, 2010, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/20084116