increased hepatocellular carcinoma incidence_Nfe2l1<tm1Jefc>/Nfe2l1<tm1Ywk>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0003331I129X1SvJC57BL6JNfe2l1tm1JefcNfe2l1tm1YwkTgAlbcre21Mgn0TgAlbcre21MgnNfe2l1tm1YwkNfe2l1tm1Jefc

increased hepatocellular carcinoma incidence_Nfe2l1<tm1Jefc>/Nfe2l1<tm1Ywk>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nuclear factor, erythroid derived 2,-like 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99421
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nfe2l1<tm1Jefc>/Nfe2l1<tm1Ywk>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Nfe2l1<tm1Ywk>|Nfe2l1<tm1Jefc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Zhenrong. Xu, et.al., Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia., Proceedings of the National Academy of Sciences of the United States of America, 2005, 102
  http://rdf.ncbi.nlm.nih.gov/pubmed/15738389