increased hepatocellular carcinoma incidence_Gtf2ird1<Tg(Alb1-Myc)166.8Sst>/0,Tg(MtTGFA)42Lmb/0

http://metadb.riken.jp/0003331IC57BL6CBACD1Gtf2ird1TgAlb1Myc1668Sst0TgMtTGFA42Lmb0Gtf2ird1TgAlb1Myc1668SstTgMtTGFA42Lmb

increased hepatocellular carcinoma incidence_Gtf2ird1<Tg(Alb1-Myc)166.8Sst>/0,Tg(MtTGFA)42Lmb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 42, Glenn Merlino
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388995
• general transcription factor II I repeat domain-containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861942

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gtf2ird1<Tg(Alb1-Myc)166.8Sst>/0,Tg(MtTGFA)42Lmb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gtf2ird1<Tg(Alb1-Myc)166.8Sst>|Tg(MtTGFA)42Lmb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• H. Murakami, et.al., Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis., Cancer research, 1993, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/8467484