increased hepatocellular carcinoma incidence_Gtf2ird1<Tg(Alb1-Myc)166.8Sst>/Gtf2ird1<+>

http://metadb.riken.jp/0003331IC57BL6CBAGtf2ird1TgAlb1Myc1668SstGtf2ird1Gtf2ird1TgAlb1Myc1668SstGtf2ird1

increased hepatocellular carcinoma incidence_Gtf2ird1<Tg(Alb1-Myc)166.8Sst>/Gtf2ird1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• general transcription factor II I repeat domain-containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861942

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gtf2ird1<Tg(Alb1-Myc)166.8Sst>/Gtf2ird1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gtf2ird1<Tg(Alb1-Myc)166.8Sst>|Gtf2ird1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Diego F. Calvisi, et.al., Activation of the canonical Wnt/beta-catenin pathway confers growth advantages in c-Myc/E2F1 transgenic mouse model of liver cancer., Journal of hepatology, 2005, 42
  http://rdf.ncbi.nlm.nih.gov/pubmed/15885355
• E. Santoni-Rugiu, et.al., Evolution of neoplastic development in the liver of transgenic mice co-expressing c-myc and transforming growth factor-alpha., The American journal of pathology, 1996, 149
  http://rdf.ncbi.nlm.nih.gov/pubmed/8701981