increased hepatocellular carcinoma incidence_Gtf2ird1<Tg(Alb1-Myc)166.8Sst>/Gtf2ird1<+>,Tg(Alb-E2F1)8Sst/0

http://metadb.riken.jp/0003331IC57BL6CBAGtf2ird1TgAlb1Myc1668SstGtf2ird1TgAlbE2F18Sst0TgAlbE2F18SstGtf2ird1Gtf2ird1TgAlb1Myc1668Sst

increased hepatocellular carcinoma incidence_Gtf2ird1<Tg(Alb1-Myc)166.8Sst>/Gtf2ird1<+>,Tg(Alb-E2F1)8Sst/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• general transcription factor II I repeat domain-containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861942
• transgene insertion 8, Snorri S Thorgeirsson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3693965

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gtf2ird1<Tg(Alb1-Myc)166.8Sst>/Gtf2ird1<+>,Tg(Alb-E2F1)8Sst/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-E2F1)8Sst|Gtf2ird1<+>|Gtf2ird1<Tg(Alb1-Myc)166.8Sst>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Diego F. Calvisi, et.al., Activation of the canonical Wnt/beta-catenin pathway confers growth advantages in c-Myc/E2F1 transgenic mouse model of liver cancer., Journal of hepatology, 2005, 42
  http://rdf.ncbi.nlm.nih.gov/pubmed/15885355