increased hepatocellular carcinoma incidence_Ddit3<tm1.1Irt>/Ddit3<tm1.1Irt>,Tg(Alb-cre)21Mgn/0,Tg(Mup3-Plau)350-2Eps/?

http://metadb.riken.jp/0003331IC57BL6DBADdit3tm11IrtDdit3tm11IrtTgAlbcre21Mgn0TgMup3Plau3502EpsTgMup3Plau3502EpsTgAlbcre21MgnDdit3tm11Irt

increased hepatocellular carcinoma incidence_Ddit3<tm1.1Irt>/Ddit3<tm1.1Irt>,Tg(Alb-cre)21Mgn/0,Tg(Mup3-Plau)350-2Eps/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• DNA-damage inducible transcript 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:109247
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• transgene insertion 350-2, Eric P Sandgren
  http://metadb.riken.jp/db/mgi_rdf/MGI:5781012

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ddit3<tm1.1Irt>/Ddit3<tm1.1Irt>,Tg(Alb-cre)21Mgn/0,Tg(Mup3-Plau)350-2Eps/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mup3-Plau)350-2Eps|Tg(Alb-cre)21Mgn|Ddit3<tm1.1Irt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Hayato. Nakagawa, et.al., ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development., Cancer cell, 2014, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/25132496