increased hepatocellular carcinoma incidence_Tg(Alb-E2F1)8Sst/0

http://metadb.riken.jp/0003331IC57BL6JCBAJTgAlbE2F18Sst0TgAlbE2F18Sst

increased hepatocellular carcinoma incidence_Tg(Alb-E2F1)8Sst/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 8, Snorri S Thorgeirsson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3693965

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Alb-E2F1)8Sst/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-E2F1)8Sst

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• E A. Conner, et.al., Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis., Oncogene, 2000, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/11042693
• Diego F. Calvisi, et.al., Activation of the canonical Wnt/beta-catenin pathway confers growth advantages in c-Myc/E2F1 transgenic mouse model of liver cancer., Journal of hepatology, 2005, 42
  http://rdf.ncbi.nlm.nih.gov/pubmed/15885355