astrocytosis_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*P101L)2866Sbp/0

http://metadb.riken.jp/0003354I129S7SvEvBrdFVBNPrnptm1CwePrnptm1CweTgPrnpP101L2866Sbp0TgPrnpP101L2866SbpPrnptm1Cwe

astrocytosis_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*P101L)2866Sbp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• prion protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97769
• transgene insertion 2866, Stanley B Prusiner
  http://metadb.riken.jp/db/mgi_rdf/MGI:5491018

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*P101L)2866Sbp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp*P101L)2866Sbp|Prnp<tm1Cwe>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• astrocytosis
  http://purl.obolibrary.org/obo/MP_0003354

文献

http://purl.org/net/cito/citesAsAuthority

• G C. Telling, et.al., Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice., Genes & development, 1996, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/8698234