increased insulinoma incidence_Men1<tm1Ctre>/Men1<tm1Ctre>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0003364I129S6SvEvTacC57BL6CBAFVBNMen1tm1CtreMen1tm1CtreTgPdx1cre891Dam0Men1tm1CtreTgPdx1cre891Dam

increased insulinoma incidence_Men1<tm1Ctre>/Men1<tm1Ctre>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318
• multiple endocrine neoplasia 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1316736

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Men1<tm1Ctre>/Men1<tm1Ctre>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Men1<tm1Ctre>|Tg(Pdx1-cre)89.1Dam

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased insulinoma incidence
  http://purl.obolibrary.org/obo/MP_0003364

文献

http://purl.org/net/cito/citesAsAuthority

• H-C Jennifer. Shen, et.al., Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1., Cancer research, 2009, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/19208834