abnormal platelet shape_Tln1<tm4.1Crit>/Tln1<tm4.1Crit>,Tg(Mx1-cre)1Cgn/?

http://metadb.riken.jp/0003405I129P2OlaHsdC57BL6CBATln1tm41CritTln1tm41CritTgMx1cre1CgnTgMx1cre1CgnTln1tm41Crit

abnormal platelet shape_Tln1<tm4.1Crit>/Tln1<tm4.1Crit>,Tg(Mx1-cre)1Cgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• talin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1099832
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tln1<tm4.1Crit>/Tln1<tm4.1Crit>,Tg(Mx1-cre)1Cgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Tln1<tm4.1Crit>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal platelet shape
  http://purl.obolibrary.org/obo/MP_0003405

文献

http://purl.org/net/cito/citesAsAuthority

• Bernhard. Nieswandt, et.al., Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo., The Journal of experimental medicine, 2007, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/18086864