decreased width of hypertrophic chondrocyte zone_Gt(ROSA)26Sor<tm1(Pim1-E2F1)Rebr>/Gt(ROSA)26Sor<+>,Tmem163<Tg(ACTB-cre)2Mrt>/0

http://metadb.riken.jp/0003409I129P2OlaHsdFVBFVBNGtROSA26Sortm1Pim1E2F1RebrGtROSA26SorTmem163TgACTBcre2Mrt0GtROSA26SorTmem163TgACTBcre2MrtGtROSA26Sortm1Pim1E2F1Rebr

decreased width of hypertrophic chondrocyte zone_Gt(ROSA)26Sor<tm1(Pim1-E2F1)Rebr>/Gt(ROSA)26Sor<+>,Tmem163<Tg(ACTB-cre)2Mrt>/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transmembrane protein 163
  http://metadb.riken.jp/db/mgi_rdf/MGI:1919410
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Pim1-E2F1)Rebr>/Gt(ROSA)26Sor<+>,Tmem163<Tg(ACTB-cre)2Mrt>/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Tmem163<Tg(ACTB-cre)2Mrt>|Gt(ROSA)26Sor<tm1(Pim1-E2F1)Rebr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased width of hypertrophic chondrocyte zone
  http://purl.obolibrary.org/obo/MP_0003409

文献

http://purl.org/net/cito/citesAsAuthority

• Blanca. Scheijen, et.al., Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation., Molecular and cellular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/12724423