renal hypoplasia_Bmp4<tm4Blh>/Bmp4<tm4Blh>,Isl1<tm1(cre)Sev>/Isl1<+>

http://metadb.riken.jp/0003446I129129S6SvEvTacBmp4tm4BlhBmp4tm4BlhIsl1tm1creSevIsl1Isl1Bmp4tm4BlhIsl1tm1creSev

renal hypoplasia_Bmp4<tm4Blh>/Bmp4<tm4Blh>,Isl1<tm1(cre)Sev>/Isl1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• bone morphogenetic protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88180
• ISL1 transcription factor, LIM/homeodomain
  http://metadb.riken.jp/db/mgi_rdf/MGI:101791

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bmp4<tm4Blh>/Bmp4<tm4Blh>,Isl1<tm1(cre)Sev>/Isl1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Isl1<+>|Bmp4<tm4Blh>|Isl1<tm1(cre)Sev>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• renal hypoplasia
  http://purl.obolibrary.org/obo/MP_0003446

文献

http://purl.org/net/cito/citesAsAuthority

• Kentaro. Suzuki, et.al., Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia., PloS one, 2012, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/23028455