decreased tumor growth/size_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0003447I129P2OlaHsd129S1Sv129X1SvJPtch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorGtROSA26SorGtROSA26Sortm2creERT2BrnPtch1tm1Hahn

decreased tumor growth/size_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• patched 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:105373

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>|Ptch1<tm1Hahn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor growth/size
  http://purl.obolibrary.org/obo/MP_0003447

文献

http://purl.org/net/cito/citesAsAuthority

• Frauke. Nitzki, et.al., Tumor stroma-derived Wnt5a induces differentiation of basal cell carcinoma of Ptch-mutant mice via CaMKII., Cancer research, 2010, 70
  http://rdf.ncbi.nlm.nih.gov/pubmed/20233865