decreased tumor growth/size_Ccnd1<tm1Wbg>/Ccnd1<tm5.1Pisc>,Tg(CAG-cre/Esr1*)5Amc/0,Tg(MMTV-Erbb2)NK1Mul/0

http://metadb.riken.jp/0003447I129S2SvPasC57BL6CBAFVBNCcnd1tm1WbgCcnd1tm51PiscTgCAGcreEsr15Amc0TgMMTVErbb2NK1Mul0TgMMTVErbb2NK1MulTgCAGcreEsr15AmcCcnd1tm51PiscCcnd1tm1Wbg

decreased tumor growth/size_Ccnd1<tm1Wbg>/Ccnd1<tm5.1Pisc>,Tg(CAG-cre/Esr1*)5Amc/0,Tg(MMTV-Erbb2)NK1Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin D1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88313
• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765
• transgene insertion NK1, William Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:3513809

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ccnd1<tm1Wbg>/Ccnd1<tm5.1Pisc>,Tg(CAG-cre/Esr1*)5Amc/0,Tg(MMTV-Erbb2)NK1Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(MMTV-Erbb2)NK1Mul|Tg(CAG-cre/Esr1*)5Amc|Ccnd1<tm5.1Pisc>|Ccnd1<tm1Wbg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * CBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor growth/size
  http://purl.obolibrary.org/obo/MP_0003447

文献

http://purl.org/net/cito/citesAsAuthority

• Yoon Jong. Choi, et.al., The requirement for cyclin D function in tumor maintenance., Cancer cell, 2012, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/23079655