decreased tumor growth/size_Ube2o<tm1.1(KOMP)Mbp>/Ube2o<tm1.1(KOMP)Mbp>,Tg(TRAMP)8247Ng/0

http://metadb.riken.jp/0003447IC57BL6C57BL6NFVBNUbe2otm11KOMPMbpUbe2otm11KOMPMbpTgTRAMP8247Ng0Ube2otm11KOMPMbpTgTRAMP8247Ng

decreased tumor growth/size_Ube2o<tm1.1(KOMP)Mbp>/Ube2o<tm1.1(KOMP)Mbp>,Tg(TRAMP)8247Ng/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 8247, Norman M Greenberg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2680364
• ubiquitin-conjugating enzyme E2O
  http://metadb.riken.jp/db/mgi_rdf/MGI:2444266

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ube2o<tm1.1(KOMP)Mbp>/Ube2o<tm1.1(KOMP)Mbp>,Tg(TRAMP)8247Ng/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ube2o<tm1.1(KOMP)Mbp>|Tg(TRAMP)8247Ng

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6N * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor growth/size
  http://purl.obolibrary.org/obo/MP_0003447

文献

http://purl.org/net/cito/citesAsAuthority

• Isabelle K. Vila, et.al., A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy., Cancer cell, 2017, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/28162974