abnormal intestinal goblet cell morphology_Tlr4<tm1Djh>/Tlr4<tm1Djh>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0003449IC57BL6C57BL6JFVBNSJLTlr4tm1DjhTlr4tm1DjhTgVil1cre997Gum0TgVil1cre997GumTlr4tm1Djh

abnormal intestinal goblet cell morphology_Tlr4<tm1Djh>/Tlr4<tm1Djh>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• toll-like receptor 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:96824
• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tlr4<tm1Djh>/Tlr4<tm1Djh>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil1-cre)997Gum|Tlr4<tm1Djh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6J * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal intestinal goblet cell morphology
  http://purl.obolibrary.org/obo/MP_0003449

文献

http://purl.org/net/cito/citesAsAuthority

• Chhinder P. Sodhi, et.al., Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice., Gastroenterology, 2012, 143
  http://rdf.ncbi.nlm.nih.gov/pubmed/22796522