abnormal keratinocyte physiology_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,E4f1<tm1Pisc>/E4f1<tm1.1Llca>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

http://metadb.riken.jp/0003453I129Sv129S4SvJaeC57BL6SJLCdkn2atm1RdpCdkn2atm1RdpE4f1tm1PiscE4f1tm11LlcaPolr2atm1creERT2BbdPolr2aE4f1tm11LlcaCdkn2atm1RdpPolr2aE4f1tm1PiscPolr2atm1creERT2Bbd

abnormal keratinocyte physiology_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,E4f1<tm1Pisc>/E4f1<tm1.1Llca>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• polymerase (RNA) II (DNA directed) polypeptide A
  http://metadb.riken.jp/db/mgi_rdf/MGI:98086
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• E4F transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109530

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,E4f1<tm1Pisc>/E4f1<tm1.1Llca>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• E4f1<tm1.1Llca>|Cdkn2a<tm1Rdp>|Polr2a<+>|E4f1<tm1Pisc>|Polr2a<tm1(cre/ERT2)Bbd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal keratinocyte physiology
  http://purl.obolibrary.org/obo/MP_0003453

文献

http://purl.org/net/cito/citesAsAuthority

• Matthieu. Lacroix, et.al., Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/21088222