increased prolactinoma incidence_Men1<tm1Gfk>/Men1<tm1Gfk>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0003505I129T2SvEmsC57BL6C57BL6JDBAMen1tm1GfkMen1tm1GfkTgIns2cre25Mgn0Men1tm1GfkTgIns2cre25Mgn

increased prolactinoma incidence_Men1<tm1Gfk>/Men1<tm1Gfk>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225
• multiple endocrine neoplasia 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1316736

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Men1<tm1Gfk>/Men1<tm1Gfk>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Men1<tm1Gfk>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129T2/SvEms * C57BL/6 * C57BL/6J * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prolactinoma incidence
  http://purl.obolibrary.org/obo/MP_0003505

文献

http://purl.org/net/cito/citesAsAuthority

• Christine A. Biondi, et.al., Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues., Molecular and cellular biology, 2004, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/15060136