abnormal vascular endothelial cell migration_Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(Tek-cre)1Ywa/0

http://metadb.riken.jp/0003544I129S1Sv129X1SvJC57BL6SJLHif1atm3RsjoHif1atm3RsjoTgTekcre1Ywa0TgTekcre1YwaHif1atm3Rsjo

abnormal vascular endothelial cell migration_Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(Tek-cre)1Ywa/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hypoxia inducible factor 1, alpha subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:106918
• transgene insertion 1, Masashi Yanagisawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450309

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(Tek-cre)1Ywa/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tek-cre)1Ywa|Hif1a<tm3Rsjo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal vascular endothelial cell migration
  http://purl.obolibrary.org/obo/MP_0003544

文献

http://purl.org/net/cito/citesAsAuthority

• Nan. Tang, et.al., Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis., Cancer cell, 2004, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/15542432