abnormal pancreatic beta cell physiology_Cacna1c<tm3Hfm>/Cacna1c<tm3Hfm>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0003562I129S1Sv129X1SvJC57BL6DBACacna1ctm3HfmCacna1ctm3HfmTgIns2cre25Mgn0TgIns2cre25MgnCacna1ctm3Hfm

abnormal pancreatic beta cell physiology_Cacna1c<tm3Hfm>/Cacna1c<tm3Hfm>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• calcium channel, voltage-dependent, L type, alpha 1C subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:103013
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cacna1c<tm3Hfm>/Cacna1c<tm3Hfm>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-cre)25Mgn|Cacna1c<tm3Hfm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic beta cell physiology
  http://purl.obolibrary.org/obo/MP_0003562

文献

http://purl.org/net/cito/citesAsAuthority

• Verena. Schulla, et.al., Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice., The EMBO journal, 2003, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/12881419