abnormal pancreatic alpha cell physiology_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>

http://metadb.riken.jp/0003563I129S1Sv129X1SvJC57BL6Pcsk2tm1DfsPcsk2tm1DfsPcsk2tm1Dfs

abnormal pancreatic alpha cell physiology_Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• proprotein convertase subtilisin/kexin type 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97512

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pcsk2<tm1Dfs>/Pcsk2<tm1Dfs>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pcsk2<tm1Dfs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic alpha cell physiology
  http://purl.obolibrary.org/obo/MP_0003563

文献

http://purl.org/net/cito/citesAsAuthority

• M. Vincent, et.al., Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased alpha-cell proliferation, and islet neogenesis., Endocrinology, 2003, 144
  http://rdf.ncbi.nlm.nih.gov/pubmed/12933680