abnormal insulin secretion_Lipe<tm2Rze>/Lipe<tm2Rze>,Tg(Ins2-cre)25Mgn/?

http://metadb.riken.jp/0003564I129C57BL6DBALipetm2RzeLipetm2RzeTgIns2cre25MgnTgIns2cre25MgnLipetm2Rze

abnormal insulin secretion_Lipe<tm2Rze>/Lipe<tm2Rze>,Tg(Ins2-cre)25Mgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lipase, hormone sensitive
  http://metadb.riken.jp/db/mgi_rdf/MGI:96790
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lipe<tm2Rze>/Lipe<tm2Rze>,Tg(Ins2-cre)25Mgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-cre)25Mgn|Lipe<tm2Rze>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal insulin secretion
  http://purl.obolibrary.org/obo/MP_0003564

文献

http://purl.org/net/cito/citesAsAuthority

• M. Fex, et.al., A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis., Diabetologia, 2009, 52
  http://rdf.ncbi.nlm.nih.gov/pubmed/19023560