increased uterus leiomyoma incidence_Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>,Pgr<tm2(cre)Lyd>/Pgr<+>

http://metadb.riken.jp/0003570I129S1Sv129X1SvJTsc2tm11MjgTsc2tm11MjgPgrtm2creLydPgrPgrTsc2tm11MjgPgrtm2creLyd

increased uterus leiomyoma incidence_Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>,Pgr<tm2(cre)Lyd>/Pgr<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tuberous sclerosis 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:102548
• progesterone receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:97567

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>,Pgr<tm2(cre)Lyd>/Pgr<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pgr<+>|Tsc2<tm1.1Mjg>|Pgr<tm2(cre)Lyd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased uterus leiomyoma incidence
  http://purl.obolibrary.org/obo/MP_0003570

文献

http://purl.org/net/cito/citesAsAuthority

• Hen. Prizant, et.al., Uterine-specific loss of Tsc2 leads to myometrial tumors in both the uterus and lungs., Molecular endocrinology (Baltimore, Md.), 2013, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/23820898