increased ovarian carcinoma incidence_Dicer1<tm1Tara>/Dicer1<tm1Tara>,Pten<tm1Hwu>/Pten<tm1Hwu>,Trp53<tm2Tyj>/Trp53<+>,Amhr2<tm3(cre)Bhr>/Amhr2<+>

http://metadb.riken.jp/0003579I129P2OlaHsd129S4SvJae129S7SvEvBrdDicer1tm1TaraDicer1tm1TaraPtentm1HwuPtentm1HwuTrp53tm2TyjTrp53Amhr2tm3creBhrAmhr2Trp53tm2TyjTrp53Ptentm1HwuAmhr2tm3creBhrDicer1tm1TaraAmhr2

increased ovarian carcinoma incidence_Dicer1<tm1Tara>/Dicer1<tm1Tara>,Pten<tm1Hwu>/Pten<tm1Hwu>,Trp53<tm2Tyj>/Trp53<+>,Amhr2<tm3(cre)Bhr>/Amhr2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• anti-Mullerian hormone type 2 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:105062
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dicer1<tm1Tara>/Dicer1<tm1Tara>,Pten<tm1Hwu>/Pten<tm1Hwu>,Trp53<tm2Tyj>/Trp53<+>,Amhr2<tm3(cre)Bhr>/Amhr2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm2Tyj>|Trp53<+>|Pten<tm1Hwu>|Amhr2<tm3(cre)Bhr>|Dicer1<tm1Tara>|Amhr2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased ovarian carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003579

文献

http://purl.org/net/cito/citesAsAuthority

• Jaeyeon. Kim, et.al., The ovary is an alternative site of origin for high-grade serous ovarian cancer in mice., Endocrinology, 2015, 156
  http://rdf.ncbi.nlm.nih.gov/pubmed/25815421