abnormal nervous system morphology_Lrrk2<tm1.1Cai>/Lrrk2<+>,Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA*A53T)E2Cai/0

http://metadb.riken.jp/0003632I129X1SvJC57BL6Lrrk2tm11CaiLrrk2TgCamk2atTA1Mmay0TgtetOSNCAA53TE2Cai0Lrrk2tm11CaiTgtetOSNCAA53TE2CaiTgCamk2atTA1MmayLrrk2

abnormal nervous system morphology_Lrrk2<tm1.1Cai>/Lrrk2<+>,Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA*A53T)E2Cai/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion E2, Huaibin Cai
  http://metadb.riken.jp/db/mgi_rdf/MGI:4420800
• transgene insertion 1, Mark Mayford
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179062
• leucine-rich repeat kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913975

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lrrk2<tm1.1Cai>/Lrrk2<+>,Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA*A53T)E2Cai/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lrrk2<tm1.1Cai>|Tg(tetO-SNCA*A53T)E2Cai|Tg(Camk2a-tTA)1Mmay|Lrrk2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal nervous system morphology
  http://purl.obolibrary.org/obo/MP_0003632

文献

http://purl.org/net/cito/citesAsAuthority

• Xian. Lin, et.al., Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein., Neuron, 2009, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/20064389