increased pancreatic beta cell number_Tg(CAG-Bgeo/ALPP)1Lbe/0,Tg(Ins2-cre/ERT)1Dam/0,Tg(Ins2-rtTA)2Efr/0,Tg(tetO-DTA)1Gfi/0

http://metadb.riken.jp/0003645I129S1Sv129X1SvJC57BL6CBATgCAGBgeoALPP1Lbe0TgIns2creERT1Dam0TgIns2rtTA2Efr0TgtetODTA1Gfi0TgIns2rtTA2EfrTgIns2creERT1DamTgCAGBgeoALPP1LbeTgtetODTA1Gfi

increased pancreatic beta cell number_Tg(CAG-Bgeo/ALPP)1Lbe/0,Tg(Ins2-cre/ERT)1Dam/0,Tg(Ins2-rtTA)2Efr/0,Tg(tetO-DTA)1Gfi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Glenn I Fishman
  http://metadb.riken.jp/db/mgi_rdf/MGI:3767621
• transgene insertion 1, Corrinne Lobe
  http://metadb.riken.jp/db/mgi_rdf/MGI:3505560
• transgene insertion 1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:3720950
• transgene insertion 2, Shimon Efrat
  http://metadb.riken.jp/db/mgi_rdf/MGI:3770666

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(CAG-Bgeo/ALPP)1Lbe/0,Tg(Ins2-cre/ERT)1Dam/0,Tg(Ins2-rtTA)2Efr/0,Tg(tetO-DTA)1Gfi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-rtTA)2Efr|Tg(Ins2-cre/ERT)1Dam|Tg(CAG-Bgeo/ALPP)1Lbe|Tg(tetO-DTA)1Gfi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic beta cell number
  http://purl.obolibrary.org/obo/MP_0003645

文献

http://purl.org/net/cito/citesAsAuthority

• Tomer. Nir, et.al., Recovery from diabetes in mice by beta cell regeneration., The Journal of clinical investigation, 2007, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/17786244