increased pancreatic beta cell number_Cdkn1b<tm1Kin>/Cdkn1b<+>,Lepr<db>/Lepr<db>

http://metadb.riken.jp/0003645IC57BL6JC57BLKSJCdkn1btm1KinCdkn1bLeprdbLeprdbLeprdbCdkn1btm1KinCdkn1b

increased pancreatic beta cell number_Cdkn1b<tm1Kin>/Cdkn1b<+>,Lepr<db>/Lepr<db>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:104565
• leptin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104993

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1b<tm1Kin>/Cdkn1b<+>,Lepr<db>/Lepr<db>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lepr<db>|Cdkn1b<tm1Kin>|Cdkn1b<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * C57BLKS/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic beta cell number
  http://purl.obolibrary.org/obo/MP_0003645

文献

http://purl.org/net/cito/citesAsAuthority

• Tohru. Uchida, et.al., Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice., Nature medicine, 2005, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/15685168