increased hemangiosarcoma incidence_Trp53<tm1Tyj>/Trp53<tm2.1Tyj>

http://metadb.riken.jp/0003667I129S2SvPas129S4SvJaeTrp53tm1TyjTrp53tm21TyjTrp53tm21TyjTrp53tm1Tyj

increased hemangiosarcoma incidence_Trp53<tm1Tyj>/Trp53<tm2.1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Tyj>/Trp53<tm2.1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm2.1Tyj>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hemangiosarcoma incidence
  http://purl.obolibrary.org/obo/MP_0003667

文献

http://purl.org/net/cito/citesAsAuthority

• Kenneth P. Olive, et.al., Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome., Cell, 2004, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/15607980