increased hemangiosarcoma incidence_Irf1<tm1Mak>/Irf1<tm1Mak>,Tg(HRAS)2Jic/?

http://metadb.riken.jp/0003667I129S2SvPasBALBcC57BL6Irf1tm1MakIrf1tm1MakTgHRAS2JicTgHRAS2JicIrf1tm1Mak

increased hemangiosarcoma incidence_Irf1<tm1Mak>/Irf1<tm1Mak>,Tg(HRAS)2Jic/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2, CIEA
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039550
• interferon regulatory factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96590

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irf1<tm1Mak>/Irf1<tm1Mak>,Tg(HRAS)2Jic/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(HRAS)2Jic|Irf1<tm1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hemangiosarcoma incidence
  http://purl.obolibrary.org/obo/MP_0003667

文献

http://purl.org/net/cito/citesAsAuthority

• H. Nozawa, et.al., Loss of transcription factor IRF-1 affects tumor susceptibility in mice carrying the Ha-ras transgene or nullizygosity for p53., Genes & development, 1999, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/10346812