oxidative stress_Nfe2l2<tm1Ywk>/Nfe2l2<tm1Ywk>

http://metadb.riken.jp/0003674I129X1SvJNfe2l2tm1YwkNfe2l2tm1YwkNfe2l2tm1Ywk

oxidative stress_Nfe2l2<tm1Ywk>/Nfe2l2<tm1Ywk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nuclear factor, erythroid derived 2, like 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:108420

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nfe2l2<tm1Ywk>/Nfe2l2<tm1Ywk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nfe2l2<tm1Ywk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• oxidative stress
  http://purl.obolibrary.org/obo/MP_0003674

文献

http://purl.org/net/cito/citesAsAuthority

• Ann F. Hubbs, et.al., Vacuolar leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2., The American journal of pathology, 2007, 170
  http://rdf.ncbi.nlm.nih.gov/pubmed/17525273
• Tobias A. Beyer, et.al., Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance., The EMBO journal, 2008, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/18059474
• Laura. Leung, et.al., Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress., The Journal of biological chemistry, 2003, 278
  http://rdf.ncbi.nlm.nih.gov/pubmed/12968018
• Jong-Min. Lee, et.al., Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/15210949