increased tumor growth/size_Egfr<wa2>/Egfr<+>,Fos<tm6.1Wag>/Fos<tm6.1Wag>,Tg(KRT5-SOS1)892A6Wag/0

http://metadb.riken.jp/0003721I129P2OlaHsdC57BL6CBASJLEgfrwa2EgfrFostm61WagFostm61WagTgKRT5SOS1892A6Wag0EgfrTgKRT5SOS1892A6WagEgfrwa2Fostm61Wag

increased tumor growth/size_Egfr<wa2>/Egfr<+>,Fos<tm6.1Wag>/Fos<tm6.1Wag>,Tg(KRT5-SOS1)892A6Wag/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• FBJ osteosarcoma oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:95574
• epidermal growth factor receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:95294
• transgene insertion 892A6, Erwin F Wagner
  http://metadb.riken.jp/db/mgi_rdf/MGI:5142259

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Egfr<wa2>/Egfr<+>,Fos<tm6.1Wag>/Fos<tm6.1Wag>,Tg(KRT5-SOS1)892A6Wag/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Egfr<+>|Tg(KRT5-SOS1)892A6Wag|Egfr<wa2>|Fos<tm6.1Wag>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor growth/size
  http://purl.obolibrary.org/obo/MP_0003721

文献

http://purl.org/net/cito/citesAsAuthority

• L. Bakiri, et.al., Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis., Oncogene, 2011, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/21119595